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”de-CIPHERing Infectious Disease” explores the cutting-edge interdisciplinary research happening at UNC Charlotte’s CIPHER Research Center. Each episode features an in-depth interview with one of CIPHER’s researchers, allowing them to discuss their background, current projects, and the exciting team science approach they take to tackle complex issues at the intersection of health, environment, data science, genomics, infectious disease, and more. Host Ian Binns engages the researchers in accessible conversations that dive into the science behind their work while also highlighting the collaborative spirit and diverse expertise that makes CIPHER’s ”One Health” philosophy so powerful. From evolution and phylogenetics to machine learning, drug discovery, and preventing the next pandemic, ”de-CIPHERing Infectious Disease” offers listeners a window into the innovative solutions being pioneered to address global challenges.
Episodes
Tuesday Feb 11, 2025
Tuesday Feb 11, 2025
Episode 12
In this conversation, Dr. Danillo Augusto shares his journey from Brazil to the US, detailing his experiences with the neglected autoimmune disease Pemphigus and his current research focus on genomic equity. He discusses the importance of studying underrepresented populations in genomics and the challenges faced in addressing health disparities.
Find out more at cipher.charlotte.edu.
Key Takeaways
- Pemphigus is a neglected autoimmune disease endemic to Brazil.
- Health disparities are evident in the lack of research on diseases affecting poor populations.
- Most genomic studies focus on European ancestry, creating gaps in understanding.
- Danilo secured a significant NIH grant to study Pemphigus.
- Understanding limitations leads to better scientific partnerships.
- Team science is essential for addressing complex research questions.
- Genetic variation in immune regions is often overlooked.
- SARS-CoV-2 research revealed strong genetic associations.
- Environmental factors can trigger health issues in populations.
- Future research should focus on underrepresented genetic regions.
This podcast was produced and edited by Zack Jackson
CIPHER is a proud part of UNC Charlotte who holds all rights to the content created by this podcast
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